Spinosad resistance affects biological parameters of Musca domestica Linnaeus

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Spinosad resistance in the housefly, Musca domestica, is due to a recessive factor on autosome 1

Spinosad is a new and highly promising insecticide with efficacy against a wide range of insects, including houseflies. Selection of the field collected houseflies produced a highly spinosad resistant (>150fold) strain of housefly following 10 generations of selection. Spinosad resistance was a recessive trait linked to autosome 1 which could not be overcome with the insecticide synergists pipe...

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Expression of Xenobiotic Metabolizing Cytochrome P450 Genes in a Spinosad-Resistant Musca domestica L. Strain

BACKGROUND Spinosad is important in pest management strategies of multiple insect pests. However, spinosad resistance is emerging in various pest species. Resistance has in some species been associated with alterations of the target-site receptor, but in others P450s seems to be involved. We test the possible importance of nine cytochrome P450 genes in the spinosad-resistant housefly strain 791...

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The nicotinic acetylcholine receptor subunits Mdα5 and Mdβ3 on autosome 1 of Musca domestica are not involved in spinosad resistance

Spinosad is a relatively new insecticide that exerts its toxic action via nicotinic acetylcholine receptors (nAChRs). Spinosad resistance in house flies appears to be due to an altered target site. To evaluate the molecular basis of spinosad resistance, two nAChR subunit genes, Mdα5 and Mdβ3 were cloned and characterized from an insecticide-susceptible (aabys) and spinosad resistant (rspin) str...

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Analysis of Differentially Expressed Genes Related to Resistance in Spinosad- and Neonicotinoid-Resistant Musca domestica L. (Diptera: Muscidae) Strains

BACKGROUND The housefly is a global pest that has developed resistance to most insecticides applied against it. Resistance of the spinosad-resistant strain 791spin and the neonicotinoid-resistant 766b strain is believed to be due to metabolism. We investigate differentially expressed genes in these two resistant strains related to metabolism in comparison with an insecticide-susceptible referen...

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Evolution of resistance to pyrethroid insecticides in Musca domestica.

Houseflies, Musca domestica L., are a significant pest because of the numerous diseases they transmit. Control of housefly populations, particularly at animal production facilities, is frequently done using pyrethroid insecticides which kill insects by prolonging the open time of the voltage-sensitive sodium channel (VSSC). Houseflies have evolved resistance to pyrethroids owing to mutations in...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2018

ISSN: 2045-2322

DOI: 10.1038/s41598-018-32445-8